心脏导电阻与心血管疾病和全因死亡率之间的关联:kailuan研究
Xuemei Yang1, Shuohua Chen2, Haicheng Song3
1Department of Rheumatic Disease, Kailuan General Hospital, Tangshan, Hebei, China; Graduate school, North China University of Science and Technology, Tangshan, Hebei, China.
International journal of cardiology
|December 23, 2023
概括
心脏导电阻 (CCB) 在一般人群中显著增加心血管疾病 (CVD) 和全因死亡率的风险. 对CCB的早期预防策略对于减少这些不良健康结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 捆绑分支阻断和心房阻断是已知的心血管疾病 (CVD) 和死亡率的风险因素.
- 更广泛的心脏导电阻 (CCB) 与心血管疾病和全因死亡率之间的特定关系尚未得到广泛的探索.
研究的目的:
- 调查心脏导电阻塞 (CCB) 与心血管疾病 (CVD) 和所有原因死亡率的发生率之间的联系.
- 评估CCB对大量人口队列中死亡率和心血管疾病事件的影响.
主要方法:
- 利用了Kailuan研究中的145,805名参与者的数据,平均随访时间为12.5年.
- 心脏导电阻 (CCB) 通过使用12导电心电图 (ECG) 来识别.
- 死亡率和心血管疾病事件通过多个综合数据源进行了跟踪.
主要成果:
- 与没有CCB的人相比,患有CCB的人群中,心血管疾病的累积发病率 (18.38%与12.14%) 和全因死亡率 (33.45%与14.18%) 较高.
- 多变量分析显示,CCB的危险比率显著增加:CVD为1.25,全因死亡率为1.31.
- 与年龄较大的参与者相比,CCB与不良结果之间的关联在年轻人中明显更强.
结论:
- 心脏导电阻塞 (CCB) 是一种独立的风险因素,与一般人群中心血管疾病 (CVD) 和全因死亡率的增加有关.
- 这些发现强调了针对CCB实施预防策略的重要性,以减轻心脏病和死亡风险.
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