P2Y2受体介导终端脂肪细胞分化和胰岛素抵抗:证据表明双G蛋白合模式

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Shenqi Qian1, Yi Shi2, Jared Senfeld2

  • 1Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama, USA; Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

The Journal of biological chemistry
|December 23, 2023
PubMed
概括

在脂肪细胞发育和炎症过程中,P2Y2受体 (P2Y2R) 被上调. P2Y2R激活通过抑制AKT信号来促进胰岛素抵抗,这表明它是肥胖和2型糖尿病治疗的目标.

关键词:
在 AKT AKT 里面.P2Y(2) 受体受体的使用情况.脂肪细胞 (adipocytes) 是一种脂肪细胞.胰岛素耐药性是一种胰岛素耐药性.肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖

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