脂肪性肝病,MASLD和患慢性病的风险
Josh Bilson1, Alessandro Mantovani2, Christopher D Byrne1
1School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health and Care Research, Southampton Biomedical Research Centre, University Hospital Southampton and University of Southampton, Southampton, UK.
与代谢功能障碍相关的脂肪性肝病 (MASLD) 越来越多地与慢性病 (CKD) 相关. 患有MASLD的个体面临着由于共同的代谢功能障碍,患上CKD的风险要高得多.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 代谢疾病 代谢疾病
背景情况:
- 与代谢功能障碍相关的脂肪肝疾病 (MAFLD) 是一个日益严重的全球健康问题.
- 该术语在2023年演变为代谢功能障碍相关的脂肪性肝病 (MASLD),包括心脏代谢风险因素.
- 人们越来越多地认识到MASLD和慢性病 (CKD) 之间的强烈关联.
研究的目的:
- 审查MASLD的诊断标准的演变.
- 检查流行病学证据,将MASLD与CKD风险联系起来.
- 讨论MASLD和CKD的机制和潜在的治疗方法.
主要方法:
- 叙事文学评论. 叙事文学评论. 叙事文学评论. 叙事文学评论.
- 对MASLD和CKD的流行病学数据的分析.
- 拟议的致病机制和治疗策略的综合.
主要成果:
- 命名体系的转变凸显了代谢功能障碍,肝病和病之间的联系.
- 患有MASLD的个人表现出明显增加发生CKD的风险.
- 共同的潜在代谢功能障碍是连接MASLD和CKD的关键因素.
结论:
- MASLD 是 CKD 发展的一个显著风险因素.
- 了解MASLD和CKD之间的联系对于患者管理至关重要.
- 对共享机制和治疗方法的进一步研究是有必要的.
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