美国严重持久性喘患者疾病负担的地理差异
Carlos A Camargo1, Pallavi B Rane2, Andrew F Beck3
1Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
概括
严重持续性喘的患病率和疾病负担在美国各州有很大差异. 喘发病结果的地理差异可能源于社会经济或环境因素,或不同的管理策略.
科学领域:
- 肺部病理学 肺部病理学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 在美国,亚国家级严重喘的地理差异未得到充分研究.
- 严重的持续性喘影响了美国人口的很大一部分.
研究的目的:
- 评估严重持久性喘患病率和特征的州级地理差异.
- 为了确定美国各州严重喘结果的差异.
主要方法:
- 使用了具有全国代表性的IQVIA医疗/药房索赔和PharMetrics Plus数据库 (2019-2020年).
- 确定的患者年龄≥12岁,患有严重的持续性喘.
- 分析了各州的患病率,恶化,喘控制,急诊,住院和生物使用情况.
主要成果:
- 严重持续性喘的患病率从19.6% (新墨西哥州) 到31.9% (阿拉斯加州) 之间.
- 恶化率从34.2% (佛蒙特州) 到45.6% (路易斯安那州) 不同;不受控制的疾病从16.5% (佛蒙特州) 到24.0% (亚利桑那州).
- 在严重不受控制的喘中,生物使用范围从2.2% (夏威夷) 到27.9% (密西西比州).
结论:
- 在美国各州的严重持续性喘患病率和疾病负担方面存在显著的地理差异.
- 这些差异的潜在原因包括社会经济因素,环境影响和喘管理的变化.
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