可能致命但很少被考虑. 在初级口腔状细胞癌中发展再养综合征的风险
Andrzej Jaxa-Kwiatkowski1, Lidia Łysenko2, Marta Gara-Rucińska3
1Department of Maxillofacial Surgery, Medical University Wroclaw, Poland.
Journal of stomatology, oral and maxillofacial surgery
|December 23, 2023
概括
营养不良的口腔癌患者面临重新养综合征 (RFS) 的风险. 高龄,低BMI和淋巴结转移预测RFS,强调需要营养评估和预防策略.
科学领域:
- 在瘤学瘤学.
- 手术营养是指手术营养.
- 内部医学 内部医学
背景情况:
- 术前和术后护理对于外科手术的结果至关重要.
- 营养不良的癌症患者需要特别注意预防复发症,如再养综合征 (RFS).
- 再养综合征是饥饿或营养不良个体营养支持的潜在致命并发症,在临床实践中经常被低估.
研究的目的:
- 评估术前口腔癌患者的营养不良和RFS风险.
- 为了确定与该人群中RFS发生相关的风险因素.
- 突出口腔癌护理中RFS预防的关键问题.
主要方法:
- 一个单一中心前性观察性研究,涉及90名患有口腔状细胞癌的患者.
- 评估营养不良和RFS风险使用国家卫生和临床卓越研究所 (NICE) 标准和NRS-2002尺度.
- 研究RFS与年龄,BMI,瘤特征,并发症,炎症标志物,/肝功能,电解质和微元素的相关性.
主要成果:
- 在晚年,较低的BMI和淋巴结转移之间发现了显著的相关性 (p <0.05),作为RFS的积极预测因素.
- 相对较低的乳酸脱酶 (LDH) 水平也被确定为RFS的预测因素.
- 在口腔癌患者中,NRS-2002尺度显示了RFS的高预测价值.
结论:
- 高龄,较低的BMI,淋巴结转移和较低的LDH是术前口腔癌患者RFS的重要危险因素.
- NRS-2002尺度是预测RFS风险的宝贵工具.
- 提高警和有针对性的营养干预措施对于预防这种脆弱患者群体的RFS至关重要.
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