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Updated: Jul 7, 2025

Techniques to Induce and Quantify Cellular Senescence
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Published on: May 1, 2017

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电离辐射通过激活NF-κB/CTCF/p16通路诱导血管光滑肌肉细胞衰老

Xuefeng Zheng1, Zhiwei Liu2, Yawen Bin3

  • 1Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.

Biochimica et biophysica acta. Molecular basis of disease
|December 23, 2023
PubMed
概括

电离辐射 (IR) 通过NF-κB/CTCF/p16通路促进血管光滑肌细胞 (VSMC) 衰老. 这项研究阐明了辐射诱导动脉样硬化背后的机制,为治疗策略提供了洞察力.

关键词:
在CTCF中,CTCF是指CTCF.在HMGB2中,它是HMGB2.电离辐射辐射的电离辐射.在 NF-κBB 中.衰老是一种衰老.在VSMC中,VSMC是VSMC.p16 p16 在这个问题上.

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