晚期肠病相关的T细胞淋巴瘤 (EATL) 呈现严重的吸收不良和同时诊断的腹腔疾病 (CD)
Anjali Rajagopal1, Carrie A Thompson2, Allison K Chorzempa3
1Department of Medicine, AI & Innovation, Mayo Clinic, Rochester, Minnesota, USA rajagopal.anjali@mayo.edu.
BMJ case reports
|December 23, 2023
概括
肠病关联的T细胞淋巴瘤 (EATL),一种侵略性的非霍奇金淋巴瘤,可以发生在患有心脏病 (CD) 的个体中. 这一案例突出显示了患有恶化吸收不良和腹痛的患者的EATL,强调需要更广泛的临床考虑.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 肠病相关的T细胞淋巴瘤 (EATL) 是一种罕见且具有攻击性的非霍奇金淋巴瘤.
- EATL与腹腔疾病 (CD) 密切相关,腹腔疾病是一种影响小肠的自身免疫性疾病.
研究的目的:
- 报告一个患者的EATL病例,该病例呈现出暗示CD的症状.
- 强调在没有先前CD诊断的情况下,在患有无法解释的胃肠道症状的患者中考虑EATL的重要性.
主要方法:
- 一个50多岁的男性患者的病例报告,腹部疼痛,无法壮成长,体重减轻.
- 诊断工作包括对CD的血清学测试,用活检进行内镜检查和CT成像.
- 十二指肠活检的组织病理学检查证实了EATL.
主要成果:
- 这位患者呈现出阳性胆固醇血清学,扩散的十二指肠缩,多发性和中腔淋巴腺病变.
- 十二指肠活检证实了EATL,IVB阶段.
- 患者接受了标准化疗方案的治疗.
结论:
- 在严重吸收不良和腹痛患者的差异诊断中应考虑EATL,特别是那些阳性腹血清学患者.
- 提高临床意识对于早期诊断和EATL的管理至关重要,不管有确定的腹腔疾病史.
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