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桃体切除术后的结局在患有粘多糖和阻塞性睡眠呼吸暂停的儿童中
Zachary Elwell1, David Mancuso2, Nikolaus E Wolter3
1Department of Otolaryngology - Head and Neck Surgery, University of Arizona College of Medicine - Tucson, 1501 N Campbell Ave, Tucson, AZ, 85724, USA. zaelwell@arizona.edu.
经过腺切除术 (AT) 的多糖症 (MPS) 儿童面临更高的呼吸问题和出血风险. 与同龄人相比,这些患者还经历了更长的住院时间和更高的治疗费用.
科学领域:
- 儿科手术 儿科手术
- 遗传学和遗传性疾病
- 医疗保健管理的管理
背景情况:
- 粘多糖症 (MPS) 是一组影响多个器官系统的罕见遗传疾病.
- 腺切除术 (AT) 是儿童常见的一种手术手术,但对于患有MPS等潜在疾病的人来说,可能会带来独特的风险.
研究的目的:
- 为了确定MPS儿童接受AT的呼吸道并发症和术后出血的发生率.
- 为了比较医院住院的时间和相关费用,对于接受AT的MPS和没有MPS的儿童.
主要方法:
- 2009年,2012年和2016年的医疗保健成本和利用项目儿童住院患者数据库 (HCUP KID) 的分析.
- 对40名患有MPS的儿童和24660名没有MPS的儿童进行AT的结果 (呼吸道并发症,出血,停留时间,成本) 的比较.
主要成果:
- 与对照组相比,患有MPS的儿童患有呼吸道并发症 (15%vs2.4%) 和手术后出血 (10%vs1.8%) 的比率明显较高.
- 患有MPS的儿童住院时间的中位数较长 (3天对1天).
- 患有MPS的儿童的医院费用要高得多 (33,016美元对15,383美元).
结论:
- 接受AT治疗的MPS儿童患有呼吸道并发症和术后出血的风险增加.
- 这些发现表明,在接受AT的MPS儿科患者中,停留时间更长,治疗费用更高.
- 这些数据可以为MPS需要AT的儿童提供术前和术后护理策略.
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