健康立场论文和氧化还原观点 - 交通噪音带来的疾病负担
Mette Sørensen1, Göran Pershagen2, Jesse Daniel Thacher3
1Work, Environment and Cancer, Danish Cancer Institute, Copenhagen, Denmark; Department of Natural Science and Environment, Roskilde University, Denmark.
Redox biology
|December 24, 2023
概括
长期暴露于交通噪音与严重的健康问题,如心脏病和糖尿病有关. 新兴研究还表明,与乳腺癌和痴呆症的联系,是由压力反应和睡眠障碍驱动的.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 交通噪音是一个广泛的城市环境暴露.
- 以前的研究将道路交通噪音与缺血性心脏病联系起来,对其他疾病的证据有限.
- 最近的研究探讨了噪音对各种疾病和潜在机制的影响.
研究的目的:
- 审查当前关于交通噪音对健康的影响的证据.
- 研究噪音引起疾病的机械路径.
- 总结有关噪音作为公共卫生风险的流行病学,临床和临床前研究结果.
主要方法:
- 流行病学,临床和临床前研究的系统审查.
- 对生理应激反应和睡眠障碍途径的分析.
- 对氧化应激,炎症和昼夜节律失调的检查.
主要成果:
- 一致的证据将道路交通噪音与缺血性心脏病,心力衰竭,糖尿病和全因死亡率的风险增加联系在一起.
- 新出现的证据表明,暴露于噪音可能会增加患乳腺癌,痴呆症和耳风险.
- 关键的机制包括生理压力,睡眠障碍,氧化压力,炎症和昼夜节律障碍.
结论:
- 交通噪音是影响公众健康的重要环境风险因素.
- 噪音引起的健康影响是由压力,睡眠障碍,氧化应激和炎症介导的.
- 需要进一步的研究和人口层面的干预措施,以减轻噪音污染对健康的负担.
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