周围静脉导管感染和失败:系统性审查和元分析
Nicole Marsh1, Emily N Larsen2, Amanda J Ullman3
1Nursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia; School of Nursing and Midwifery, School of Medicine, Griffith University, Nathan, Queensland, Australia; Menzies Health Institute Queensland, Brisbane, Queensland, Australia; Alliance for Vascular Access Teaching and Research, Griffith University, Brisbane, Queensland, Australia; Nursing, Midwifery and Social Work, The University of Queensland, St Lucia, Queensland, Australia.
外周静脉导管失效影响了三分之一的器件,构成了全球重大挑战. 虽然感染率很低,但大量使用意味着感染和故障仍然会对患者造成重大伤害和医疗费用.
科学领域:
- 医疗器械安全 医疗器械安全
- 传染病流行病学 传染病流行病学
- 护理实践 护理实践
背景情况:
- 周围静脉导管 (PIVC) 在医疗保健中无处不在,但容易出现并发症.
- 常见的并发症包括感染和设备过早故障.
- 了解这些问题的普遍性对于患者安全至关重要.
研究的目的:
- 系统地审查和确定PIVC感染的流行率.
- 为了确定所有原因的PIVC失败的流行率.
- 综合目前关于PIVC相关并发症的证据.
主要方法:
- 对观察性研究和随机对照试验的系统审查.
- 从2000年开始在主要数据库 (科克兰图书馆,PubMed,CINAHL,EMBASE) 进行的搜索.
- 使用随机效应模型进行元分析,以组合流行率估计.
主要成果:
- 分析包括41个观察性研究和28个RCT,包括478,586个PIVC.
- 与导管相关的血液感染的整体比例为0.028%;局部感染为0.150%.
- 所有原因的PIVC衰竭发生在36.4%的病例中,每100个导管日发生率为4.42.
结论:
- PIVC故障是一个广泛的问题,影响了超过三分之一的导管.
- 虽然每个导管的感染率很低,但全球范围内的使用导致了高绝对数量的感染.
- 系统性干预对于缓解PIVC感染和失败,减少治疗中断,成本和改善患者治疗结果至关重要.
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