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Updated: Jul 7, 2025

A High-content Assay for Monitoring AMPA Receptor Trafficking
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A High-content Assay for Monitoring AMPA Receptor Trafficking

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在阿尔茨海默氏病中的突触可塑性和记忆中,GluA3和Epac2之间的新型交叉通道机制在突触可塑性和记忆中

Tong Zhang1, Amalia M Dolga2, Ulrich L M Eisel3

  • 1Department of Molecular Pharmacology, University of Groningen, the Netherlands; Department of Molecular Neurobiology, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen 9747 AG, Netherlands.

Neurobiology of disease
|December 24, 2023
PubMed
概括

阿尔茨海默病通过破坏GluA3受体和循环腺单酸盐 (cAMP) 途径,损害记忆力. 本综述探讨了GluA3和Epac2在阿尔茨海默病中的突触可塑性和记忆缺陷中的作用.

关键词:
亚马帕尔 (AMPAR) 是一个亚马帕尔 (AMPAR).阿尔茨海默病的疾病阿尔茨海默病的疾病.这就是Epac2的意思.在 GluA3A3 中.记忆 记忆 记忆 记忆 记忆突触性可塑性 突触性可塑性cAMPP 这是一个很棒的平台.

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