估计的脉冲波速度与心力衰竭患者全因死亡之间的关联
Xiang Yuan1, Chun-Wei Chen2, Jian Mao3
1Department of Emergency Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Revista clinica espanola
|December 24, 2023
概括
通过估计脉冲波速度 (ePWV) 测量的动脉硬与心力衰竭患者的死亡率增加有关. 较高的ePWV表明风险更高,强调其在管理心力衰竭结果中的重要性.
科学领域:
- 心脏病学 心脏病学
- 血管医学 血管医学
- 公共卫生 公共卫生
背景情况:
- 动脉样硬化是心力衰竭发展和再入院的已知危险因素.
- 估计脉冲波速度 (ePWV) 是一种新的,非侵入性的动脉硬度指标.
研究的目的:
- 调查诊断为心力衰竭的患者EPWV和全因死亡率之间的关系.
- 评估动脉硬在心力衰竭管理中的预后价值.
主要方法:
- 一项使用1999-2018年NHANES数据的队列研究,包括1272名心力衰竭患者.
- 分析涉及将ePWV分类为三元体,使用卡普兰-梅尔生存曲线,平滑曲线拟合和COX回归.
- 调整的危险比率 (HR) 被计算出来,以确定ePWV水平与死亡率之间的关联.
主要成果:
- 较高的ePWV水平与心力衰竭患者全因死亡率的增加有关.
- 在多变量调整后,增加的ePWV与死亡率呈现积极关联 (HR = 1.17,95% CI: (1.12,1.22)).
- 与最低三分之一相比,ePWV的最高三分之一具有1.81的多变量调整HR (95%CI: (1.45, 2.27)).
结论:
- 估计的脉冲波速度 (ePWV) 与心力衰竭患者的全因死亡率有关.
- 在这种患者群体中,ePWV作为死亡率的重要预测指标.
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