实施针对免疫媒介炎症疾病的个性化饮食干预措施
Thomas G Guilliams1, Jill Weintraub2
1Scientific Director -AndHealth- Columbus, Ohio; Founder/Director of the Point Institute- Stevens Point, Wisconsin; Adj. Associate Professor- School of Pharmacy, Univ. of Wisconsin-Madison.
Integrative medicine (Encinitas, Calif.)
|December 25, 2023
概括
饮食模式影响慢性疾病,包括免疫媒介性炎症性疾病 (IMID). 个性化营养,考虑到肠道健康和免疫反应,为IMIDs提供了基础辅助治疗.
科学领域:
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 饮食模式和慢性疾病之间存在确定的流行病学联系,包括自身免疫和免疫媒介炎症疾病 (IMIDs).
- 评估个体风险和确定影响IMIDs的特定饮食成分仍然是复杂和有争议的.
- 在IMID中饮食干预的临床试验结果往往含糊不清,导致有限的指导方针建议和临床实践采用.
研究的目的:
- 总结有关饮食模式,个人饮食评估和针对特定IMID的干预措施的已公布数据.
- 突出有关肠道微生物组,肠道透性和免疫反应力的新兴数据在饮食干预中的作用.
- 倡导个性化的营养干预作为慢性免疫介导炎症的基础治疗.
主要方法:
- 综述已发表的文献,将饮食模式,个人饮食评估和IMIDs的饮食干预措施联系起来.
- 对链接饮食,肠道微生物组,肠道透性和免疫反应性机制的新兴数据的分析.
- 综合证据支持IMID的个性化营养策略.
主要成果:
- 饮食模式显著影响慢性疾病风险,包括IMIDs.
- 涉及肠道微生物组,肠道透性和免疫反应性的机制是了解饮食在IMIDs中的作用的关键.
- 个性化的营养干预,以及其他生活方式的改变,显示作为基础治疗的承诺.
结论:
- 个性化的饮食评估和建议对于利用IMIDs中食品驱动炎症的新兴数据至关重要.
- 营养干预应该被认为是慢性免疫介导炎症的基础治疗,当个性化和与生活方式改变相结合时.
- 解决食物驱动系统性炎症的复杂性需要专门的营养专业知识,以有效管理IMID.
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