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基于多电解质的固体分散剂,以提高西尔代纳菲尔酸盐的溶解和pH独立的受控释放

Ju-Hyeong Woo1, Hai V Ngo1, Hy D Nguyen1

  • 1College of Pharmacy, Ajou University, Suwon 16499, Republic of Korea.

Heliyon
|December 25, 2023
PubMed
概括

这项研究开发了一种使用固体分散和多电静态相互作用的新型矩阵片来实现提升,pH独立的西尔德纳菲尔酸盐 (SIL) 释放. 这种方法可以改善溶解和生物可用性,使难以溶解的药物.

关键词:
有控制释放的释放.不同电荷的聚合物.增强的溶解方式多电静相互作用的多电静相互作用.西尔德纳菲尔酸盐是什么基于Soluplus®的固体分散剂

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