相关实验视频

Updated: Jul 7, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

Published on: June 6, 2025

使用恩特雷克提尼布进行的HSCT后维持治疗,用于AML患者,伴随着ETV6::NTRK3:一个病例报告

Xiaoli Zhao^1,2, Mengze Hao^1,2, Xiaoyu Zhang^1,2

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300020, People's Republic of China.

OncoTargets and therapy

|December 25, 2023

概括

神经受体氨酸激酶 (NTRK) 基因融合在血液癌症中很罕见. 一名耐火性急性髓性白血病患者在干细胞移植后获得了因特雷克提尼布维护的缓解,标志着首次成功使用干细胞移植后的TRK抑制剂.

科学领域:

在瘤学瘤学.
血液学血液学血液学
分子生物学分子生物学

背景情况:

神经营养受体氨酸激酶 (NTRK) 基因融合是各种固体瘤中的致癌驱动因素.
热胺受体激酶 (TRK) 抑制剂在NTRK融合阳性癌症中表现出显著的抗瘤活性.
在血液性恶性瘤中很少报告NTRK融合,临床数据有限.

关键词:

ETV6::NTRK3 在线播放急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.全源性造血干细胞移植造血干细胞移植恩德雷克提尼布 (Entrectinib) 是一种药物.

更多相关视频

Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma

Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma

Published on: October 27, 2014

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography

Published on: February 17, 2022

相关概念视频