患有肌肉道综合征和决定因素导致的慢性疼痛的患者的中心敏感性
Beibei Feng1,2,3,4, Chen Gong1,3,4, Longfei You1,3,4
1Department of Rehabilitation Medicine, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Journal of pain research
|December 25, 2023
概括
中枢敏感性 (CS) 常见于手腕道综合征 (CTS) 患者,经常伴有神经病痛和焦虑. 更高的自我感知总体健康与较低的CS患病率有关.
科学领域:
- 神经学 神经学
- 疼痛医学 医学 疼痛医学
- 临床研究 临床研究
背景情况:
- 中枢敏感性 (CS) 是慢性疼痛的一个已知的因素,但其在手管综合征 (CTS) 中的作用尚不清楚.
- 在CTS中调查CS和神经病痛对于了解患者体验至关重要.
研究的目的:
- 调查手腕道综合征 (CTS) 患者中中央敏感化 (CS) 和疼痛概况的流行情况.
- 为了确定与CTS患者中CS相关的潜在决定因素.
主要方法:
- 用临床评估和神经传导研究来评估怀疑CTS和健康对照患者.
- 中央敏感化库存 (CSI) 对CS进行了选,同时对神经病痛,症状严重程度,情绪状态和生活质量进行了评估.
- 后勤回归分析确定了与CS存在相关的因素.
主要成果:
- 超过60%的CTS患者表现出临床CS,明显高于对照组.
- 超过70%的CTS患者患有神经病痛成分,四分之一的人患有抑郁或焦虑.
- 焦虑与CS风险增加有关 (OR=1.31),而更好的自我感知一般健康与较低的CS相关 (OR=0.92).
结论:
- 中枢敏感性 (CS) 在手掌道综合征 (CTS) 患者中很普遍,通常与神经病痛和心理困扰同时发生.
- 焦虑与CS在CTS中显著相关,自我感知的一般健康与CS相反相关.
- 需要进一步的研究,以了解焦虑和中央疼痛处理在疼痛性陷入神经病变 (如CTS) 中的相互作用.
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