在适应性肺透气后探索COVID-19相关肺纤维化中的预后显著因素
Mirkhoshim Mirsaliyev1, Khadisha Kashikova2, Aisulu Zholdybayeva2
1KazNMU named S.D. Asfendiyarov, Almaty, Kazakhstan.
Medical journal of the Islamic Republic of Iran
|December 25, 2023
概括
超过一半的COVID-19幸存者在8个月内恢复肺功能,但肺纤维化仍然是一个问题. 识别年龄和IL-6水平等危险因素对于管理长期COVID并发症至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 放射学 放射学是一门学科.
背景情况:
- 住院COVID-19幸存者经常经历持续的症状和放射性异常.
- 肺纤维化 (PF) 和依赖氧气对于大量患者来说是预期的长期后果.
- 了解纤维变化的风险因素和CT与功能结果的相关性至关重要.
研究的目的:
- 在COVID-19住院后的患者中描述持续的肺部后果.
- 确定COVID-19后肺纤维化病的临床,放射学和实验室预测因素.
主要方法:
- 在2020年11月至12月期间接受治疗的77名COVID-19幸存者的回顾性评估.
- 高分辨率计算机断层扫描 (CT) 在急性阶段和出院后6-8个月的评估.
- 根据放射性纤维化样异常与疾病解决方案对队列进行分类.
主要成果:
- 常见的CT检测结果包括对酶体绳索,不规则的接口,网化和引支气管.
- 肺纤维化样变化持续在49.35%的患者在出院6-8个月后.
- 年龄,BMI,高IL-6,低IO水平和机械通风是持续性肺纤维化的预后指标.
结论:
- 在超过一半的COVID-19患者中,肺功能可以在8个月后恢复正常.
- 在管理COVID-19的长期影响,特别是肺纤维化方面存在重大知识差距.
- 持续的研究和临床试验对于解决COVID-19后纤维化和预防死亡至关重要.
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