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美国医疗补助计划中肝炎C病毒药物的使用,补偿和价格趋势:2001-2021年
Musaab H Gari1, Abdulrahman Alsuhibani1,2, Amin Alashgar1,2
1James L. Winkle College of Pharmacy, University of Cincinnati Academic Health Center, Cincinnati, OH 45267, USA.
Exploratory research in clinical and social pharmacy
|December 25, 2023
概括
针对型肝炎病毒 (HCV) 治疗的直接作用抗病毒 (DAA) 药物产生了比传统疗法更高的补偿,尽管价格很高. 治疗指南和政策显著影响了这些趋势,影响了可访问性.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 药物经济学 药物经济学
- 公共卫生 公共卫生
背景情况:
- 肝炎C病毒 (HCV) 仍然是一个全球健康挑战,发病率不断增加.
- 直接作用抗病毒剂 (DAA) 提供治疗方法,但面临利用和可访问性问题.
研究的目的:
- 分析2001-2021年美国HCV治疗的使用,报销和价格趋势.
- 评估治疗指南和政策对HCV药物趋势的影响.
主要方法:
- 使用门诊药房数据 (2001-2021) 进行回顾性药物利用研究.
- 对常规疗法 (CT) 和DAA药物的处方数量,报销和价格的分析.
- 随着时间的推移,对HCV治疗指南,政策和立法进行评估.
主要成果:
- 尽管总利用率较低,但DAA代理商的报销额明显高 (19.45亿美元) 比CT (4.1亿美元).
- 像索福斯布维尔和莱迪帕斯维尔/索福斯布维尔这样的DAA药物平均处方价格高 (分别为24,992美元和22,787美元).
- DAA代理商取代了CT,导致市场竞争,但价格仍然很高.
结论:
- 高昂的DAA药物价格可能会导致可访问性问题,这可以通过增加HCV发病率来证明.
- 治疗指南和政策是影响HCV治疗趋势和可访问性的关键因素.
- 对DAA代理可访问性的成本有效策略进行进一步研究是有必要的.
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