在中国宁波的2型糖尿病患者中,体力活动与动脉硬之间的关联:一项跨部门研究
Xueyu Li1, Kaushik Chattopadhyay2, Xiaoting Chen3
1Department of Endocrinology and Metabolism, The First Affiliated Hospital of Ningbo University, Ningbo, People's Republic of China.
Diabetes, metabolic syndrome and obesity : targets and therapy
|December 25, 2023
概括
定期体育活动与2型糖尿病 (T2DM) 患者的动脉硬性降低有关. 这项研究强调了运动对于管理T2DM患者的血管健康的重要性.
科学领域:
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
- 运动生理学 运动生理学
背景情况:
- 动脉硬是心血管疾病的重要危险因素,特别是在2型糖尿病 (T2DM) 患者中.
- 了解影响T2DM动脉硬性的可修改因素,如身体活动,对于开发有效的管理策略至关重要.
- 以前的研究表明,身体活动和血管健康之间存在联系,但中国T2DM患者的具体数据有限.
研究的目的:
- 调查T2DM诊断的成年患者不同程度的体力活动与动脉硬之间的关联.
- 量化国际体育活动问卷 (IPAQ) -Short测量的体力活动与动脉硬指标之间的关系,包括臂脉冲波速度 (baPWV) 和常见动脉内心介质厚度 (CCA IMT).
主要方法:
- 一项横截面研究利用了来自代谢管理中心 (MMC) 数据集 (2018年3月 - 2023年2月) 的4444名成年T2DM患者的数据.
- 根据IPAQ-Short得分,身体活动被分为高,中和低.
- 使用baPWV (≥1800cm/s) 和CCA IMT (≥1mm) 的定义值来评估动脉硬度. 进行了多次物流回归分析.
主要成果:
- 显著比例的T2DM患者表现出低 (46.5%) 或中度 (47.0%) 的身体活动水平,只有6.5%报告高活动.
- 动脉硬度很普遍,根据baPWV影响了18.8%的患者,根据CCA IMT影响了17.5%.
- 具有中度至高体力活动的患者显示动脉硬的几率明显较低 (基于baPWV:OR 0.82,0.58),高体力活动与基于CCA IMT (OR 0.49) 的动脉硬的几率较低有关.
结论:
- 较高的体力活动水平与中国宁波T2DM患者的动脉硬性降低有显著关联.
- 这些发现强调了促进体育活动对于T2DM患者血管健康管理的重要性.
- 建议进行进一步的纵向研究,以确认这些关联并探索因果关系.
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