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埃泽蒂米布改善了西斯胺诱导的毒性:通过调节AMPK/Nrf2/TXNIP信号传递来实现一种新的治疗方法

Nevine Fathy1, Shaimaa Farouk1, Rabab H Sayed2,3

  • 1Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|December 25, 2023
PubMed
概括

埃泽蒂米布通过激活AMPK和Nrf2通路来保护对抗西斯普拉丁诱导的损伤. 这种抗高脂药物可以减少氧化应激,炎症和亡,为毒性提供潜在的治疗策略.

关键词:
通过AMPK/Nrf2/HO-1通道.在TXNIP/ASK1信号传输中.在TXNIP/NLRP3信号传输中.锡斯普拉丁诱导的脏毒性埃塞蒂米贝贝是什么意思

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