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Matteo Castelli1, Andrea Magni1, Giorgio Bonollo1

  • 1Dipartimento di Chimica, Università di Pavia, Pavia, Italy.

概括

分子辅助子Hsp90和Hsp70使用ATP循环和辅助子来折叠像葡萄糖皮质受体 (GR) 这样的客户端蛋白质. 这项研究揭示了它们的动态相互作用如何调节GR折叠和成熟.

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