Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Glial Cells01:04

Glial Cells

87.3K
Overview
87.3K
Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

3.0K
Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...
3.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Glia orchestrate neural circuit development.

Developmental cell·2026
Same author

Neuroligin-2 is ubiquitinated by Nedd4l to control developmental astrocyte morphogenesis.

The Journal of cell biology·2026
Same author

δ-catenin controls layer-specific transcriptional maturation of astrocytes via Zbtb20.

bioRxiv : the preprint server for biology·2026
Same author

Reprogramming of neuronal genome function and phenotype by astrocytes.

bioRxiv : the preprint server for biology·2026
Same author

Astrocyte-microglia crosstalk through Hevin and Toll-like receptor signaling controls developmental thalamocortical synapse refinement.

Neuron·2026
Same author

Phosphatidylserine exposure by developing astrocytes initiates microglia-mediated developmental cell death.

bioRxiv : the preprint server for biology·2026

相关实验视频

Updated: Jul 7, 2025

Analysis of Schwann-astrocyte Interactions Using In Vitro Assays
10:17

Analysis of Schwann-astrocyte Interactions Using In Vitro Assays

Published on: January 13, 2011

12.3K

在多发性硬化症中天体细胞信号和相互作用.

Crystal Colón Ortiz1, Cagla Eroglu2

  • 1Department of Cell Biology, Duke University Medical Center, Durham, NC, 27710, USA.

Current opinion in cell biology
|December 25, 2023
PubMed
概括

星球细胞是一种质细胞,在多发性硬化症 (MS) 中发挥关键作用,通过改变信号和细胞相互作用显著影响脱和髓修复.

更多相关视频

An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices
06:36

An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices

Published on: February 5, 2015

7.1K
Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning
11:11

Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning

Published on: February 17, 2016

11.9K

相关实验视频

Last Updated: Jul 7, 2025

Analysis of Schwann-astrocyte Interactions Using In Vitro Assays
10:17

Analysis of Schwann-astrocyte Interactions Using In Vitro Assays

Published on: January 13, 2011

12.3K
An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices
06:36

An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices

Published on: February 5, 2015

7.1K
Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning
11:11

Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning

Published on: February 17, 2016

11.9K

科学领域:

  • 神经科学是一个神经科学.
  • 免疫学 免疫学 免疫学
  • 细胞生物学 细胞生物学

背景情况:

  • 多发性硬化症 (MS) 是成年人残疾的主要原因,其特征是神经炎症和髓损伤.
  • 目前的研究往往强调在MS病原和修复中的外周免疫细胞.
  • 新出现的证据突出显示了星球细胞在多发性硬化症中的关键作用.

研究的目的:

  • 审查最近关于MS中天体细胞信号变化的发现.
  • 探索这些变化如何影响天体细胞与其他神经细胞的相互作用.
  • 了解星球细胞对MS中脱髓化和髓修复的贡献.

主要方法:

  • 对MS中星球细胞的最新科学文献的综述.
  • 对天体细胞的转录和形态变化的分析.
  • 检查信号通路和涉及星体细胞的细胞相互作用.

主要成果:

  • 天体细胞在MS中表现出显著的形态和转录基因变化.
  • 这些变化会影响天体细胞介导的信号传递.
  • 改变的天体细胞信号影响它们与神经元和其他质细胞的相互作用,影响脱和修复.

结论:

  • 星球细胞是MS病理生理学的关键参与者,而不仅仅是被动的旁观者.
  • 了解MS中天体细胞信号传递对于开发新的治疗策略至关重要.
  • 准特定的天体细胞通路可能为MS治疗提供新的方法.