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Updated: Jul 7, 2025

Polyacrylamide Gels for Invadopodia and Traction Force Assays on Cancer Cells
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一个协同调节在HCC的矩阵刚性驱动的入侵形成中起作用

Xi Zhang1, Yingying Zhao1, Miao Li1

  • 1Liver Cancer Institute, Zhongshan Hospital, Fudan University & Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, 180 Feng Lin Road, Shanghai, 200032, PR China.

Cancer letters
|December 25, 2023
PubMed
概括

增加的矩阵刚度通过促进invadopodia形成来增强肝细胞癌 (HCC) 细胞入侵. 这通过结合的机械和生化信号通路发生,揭示了HCC进展中的新型调节机制.

关键词:
肝细胞癌 (HCC) 是一种肝细胞癌.集成蛋白 β1 的作用.在 Invadopodia 中,我们发现了矩阵的刚度 矩阵的刚度这是一个Piezo1.

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