对心脏移植后的认知功能,疾病感知和免疫抑制药物坚持的横截面研究
Stacy Al-Saleh1, Samantha Conley2, Thaddeus Pace3
1Mayo Clinic, Phoenix, AZ, USA.
Western journal of nursing research
|December 26, 2023
概括
认知功能和疾病感知影响心脏移植接受者的药物坚持. 提高记忆力和对疾病的理解有助于坚持,突出了针对性干预的需要.
科学领域:
- 心脏病学 心脏病学
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
背景情况:
- 有限的研究存在于认知功能,疾病感知和心脏移植后的药物坚持.
- 这种差距阻碍了开发有效的干预措施,以改善遵守.
研究的目的:
- 描述心脏移植接受者的认知功能,疾病感知和药物坚持之间的关系.
主要方法:
- 进行了一项横截面的观察性研究.
- 关键措施包括认知评估 (t-MoCA©,成人认知简要测试),抑郁查 (PHQ-9),坚持 (巴塞尔评估) 和疾病感知 (简要疾病感知问卷).
- 统计分析涉及描述性统计,相关性和后勤回归.
主要成果:
- 31.4%的参与者不坚持使用免疫抑制药物.
- 更好的情节性记忆和更高的疾病连贯性得分与没有错过的药物剂量相关.
- 正常的认知功能 (较高的t-MoCA©得分) 和较低的抑郁症得分与及时服用药物有关.
- 超过22%的人表现出轻度认知障碍 (t-MoCA©分数<19).
结论:
- 在心脏移植患者中,认知障碍可能被低估.
- 特定的认知领域和疾病感知与药物坚持有关.
- 未来的研究应该探索纵向变化,并为这个人群提供干预设计的信息.
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