淋巴结膜炎的患病率和模式:马来西亚两个三级中心的经验
Sadiq Maifata1, Rafidah Hod2, Fauzah Abd Ghani3
1Federal University of Lafia, Nasarawa, Nigeria.
概括
淋巴结膜炎 (GN) 患病率,特别是膜性淋巴结膜 (MGN),正在发生变化. 狼性炎和免疫球蛋白A脏病是马来西亚分别是二级和初级GN的关键原因.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 病理学 病理学 病理学
背景情况:
- 淋巴结膜炎 (GN),特别是膜性淋巴结膜炎 (MGN) 的患病率呈现时间变化.
- 影响GN患病率的因素包括遗传学,环境,种族,年龄和活检指示.
研究的目的:
- 评估GN的分布和变化模式.
- 评估膜性GN (MGN) 和其亚型 (初级与二级) 的患病率.
主要方法:
- 从2012年1月到2019年10月,对1000123个脏活检进行了回顾性分析.
- 利用电子显微镜,免疫组织化学和临床数据来区分初级和二级MGN.
- 分类GN原因,包括狼性炎 (LN) 和糖尿病.
主要成果:
- 主要MGN占MGN病例的64.8%,次要MGN占MGN病例的35.2%.
- 狼性炎 (LN) 是二次性GN (44.2%) 的最常见原因,其次是糖尿病 (25.6%).
- 马来西亚的免疫球蛋白A脏病和LN分别是导致初级和二级GN的主要原因.
结论:
- 来自马来西亚的脏活检数据揭示了不断演变的GN流行模式.
- MGN的流行率及其初级/二级分布显示出显著的趋势.
- 了解这些模式对于管理该地区的天然气至关重要.
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