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退行性胸部骨髓病变:流行病学,遗传学和病变发生的范围审查
Tanzil Rujeedawa1, Oliver D Mowforth1, Benjamin M Davies1
1Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Global spine journal
|December 26, 2023
概括
退行性胸部骨髓病变 (DTM) 包含各种脊髓疾病. 引入像DTM和退行性脊髓病 (DSM) 这样的标准化术语可以改善临床识别和沟通.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 脊髓医学 脊髓医学
背景情况:
- 胸脊髓骨髓病变由于具有相似临床特征的多种病因,提出了诊断和管理方面的挑战.
- 对于退行性宫骨髓病 (DCM) 的标准化术语的成功凸显了在脊髓疾病中需要一致的命名的需要.
- 目前胸部骨髓病的术语是分散的,阻碍了研究和临床共识.
研究的目的:
- 倡导采用标准化术语用于胸部骨髓病变.
- 建议将退行性胸部骨髓病变 (DTM) 和退行性脊髓病变 (DSM) 作为一个总体术语.
- 增强胸部骨髓病领域的认可,沟通和研究.
主要方法:
- 按照PRISMA指南进行了系统的文献搜索.
- 搜索的数据库包括Embase和MEDLINE.
- 审查的重点是确定与退行性胸部骨髓病相关的文献.
主要成果:
- 退行性胸部骨髓损伤 (DTM) 包括诸如胸部脊髓损伤,带骨化/缩,退行性磁盘疾病,骨关节炎,磁盘,骨质植物病等疾病.
- 常见的临床表现包括腰带疼痛,步态障碍,腿部虚弱,感官缺陷和膀/肠道功能障碍,通常伴有背痛.
- 手术干预通常是适用的,结果受到病因病理和脊柱狭窄的影响.
结论:
- 包括DTM在内的临床条件是相互关联的,可以共存,并分享类似的表现.
- 为DTM和DSM采用类似于DCM的统一命名法,将促进更好的理解和合作.
- 标准化术语对于推进研究优先事项和改善胸肌病患者护理至关重要.
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