两年自闭症风险查和三年非常早产婴儿的发育结果
Coral L Shuster1, Stephen J Sheinkopf2, Elisabeth C McGowan1,3
1The Brown Center for the Study of Children at Risk, Women and Infants Hospital, Providence, Rhode Island.
JAMA pediatrics
|December 26, 2023
概括
幼儿自闭症修改后检查清单,修订后跟踪 (M-CHAT-R/F) 有效地查非常早产婴儿的发育迟缓. 2岁时的阳性查预测了3岁时显著的认知,语言和运动缺陷.
科学领域:
- 发育儿科 发育儿科
- 新生儿科学 新生儿科学
- 儿童心理学 儿童心理学
背景情况:
- 幼儿自闭症修改检查清单,修订后跟踪 (M-CHAT-R/F) 是一个双阶段的家长报告自闭症风险查工具.
- 人们对M-CHAT-R/F的敏感性和特异性存在担忧.
- 它在非常早产婴儿中的实用性要求对儿科护理环境进行调查.
研究的目的:
- 评估2岁时使用M-CHAT-R/F进行自闭症风险查和3岁时在非常早产婴儿中随后的行为和发育结果之间的关联.
主要方法:
- 对非常早产婴儿 (出生时<30周妊娠年龄) 进行了一项纵向的多站点队列研究.
- 在2岁时进行了M-CHAT-R/F.
- 认知,语言和运动发育 (贝利婴幼儿发展尺度,第三版) 和行为结果 (儿童行为检查清单) 在3岁时被评估.
主要成果:
- 在467名非常早产婴儿中,有10.9%的婴儿在2岁时在M-CHAT-R/F检查中呈阳性.
- 阳性查与3岁时贝利-III的较低的认知,语言和运动复合分数显著相关.
- 阳性查还预测了CBCL内部化,外部化和普遍发育障碍等级的更高得分.
结论:
- 在2岁时使用的M-CHAT-R/F作为一个有意义的查,用于识别非常早产婴儿的发育迟缓.
- 该工具有效地识别了在3岁时发现的具有重大发育和行为问题的风险的婴儿.
- 这些发现支持在儿科环境中继续使用M-CHAT-R/F来监测非常早产的婴儿.
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