在温和条件下形成的超性和抗摩擦薄水凝,用于医疗裸金属导线
Guangyao Yang1,2, Weihao Lin1,2, Basit Ali Shah1
1School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, P. R. China.
ACS applied materials & interfaces
|December 26, 2023
概括
研究人员开发了一种用于医疗导线的新型水凝涂层,显著减少摩擦并提高耐用性. 这项创新提高了血管内干预治疗程序的安全性和性能.
科学领域:
- 生物材料科学 生物材料科学
- 医疗设备工程 医疗设备工程
- 聚合物化学 聚合物化学
背景情况:
- 医疗导线对于血管内干预治疗至关重要.
- 裸金属导线需要滑性和耐用涂层,以防止组织损伤.
- 在不同的金属基板和聚合物涂层之间实现强的粘附仍然具有挑战性.
研究的目的:
- 介绍各种医疗导线的环保水凝涂层方案.
- 开发一种在温和条件下的制备方法,以提高涂层性能.
- 为了提高导线的滑性和耐用性,用于血管内手术.
主要方法:
- 一个多步骤的过程,涉及表面预处理 (低温加热,化),浸泡涂层和UV聚合.
- 在导线基板上形成一个相互透的交叉连接的水凝网络.
- 测试涂层的超性,滑性,粘附性和摩擦阻力.
主要成果:
- 水凝涂层表现出超性,并在三种不同的金属线上显著减少摩擦 (≥95%).
- 薄涂层 (<6.2微米) 具有强大的粘附性和耐用性,可承受高达125个摩擦周期.
- 涂层的复合NiTi导线满足了临床摩擦要求 (25个周期的0.183N).
结论:
- 开发的水凝涂层方案为医疗导线提供了出色的滑性和耐用性.
- 该制备方法对各种金属基板和环保意识有效.
- 这项技术在推进血管内干预治疗设备方面具有重大潜力.
更多相关视频
08:39Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release
Published on: July 4, 2017
8.9K
08:17An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
Published on: July 18, 2018
7.2K
相关概念视频
Preparation of Samples for Electron Microscopy
To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...
Colloidal precipitates
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
Coagulation
Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...
