在患有不同类型心力衰竭的急性缺血性中风患者之间比较特征和结果
Jiongxing Wu1,2, Mingxi Chen1,2, Huan Wang1,2
1Department of Neurology, West China Hospital, Sichuan University.
International heart journal
|December 26, 2023
概括
患有急性缺血性中风 (AIS) 和心力衰竭与保留喷射率 (HFpEF) 的患者面临的结果比心力衰竭与减少喷射率 (HFrEF) 患者更糟糕. 这凸显了对AIS后的HFpEF患者进行量身定制的监测和管理策略的需要.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 脑卒中医学 脑卒中医学
背景情况:
- 急性缺血性中风 (AIS) 可以通过心力衰竭与保存的喷射率 (HFpEF) 或心力衰竭与减少的喷射率 (HFrEF) 复杂化.
- 在AIS之后,这两种心力衰竭类型之间的比较预后尚未确立.
研究的目的:
- 为了比较AIS患者HFpEF与HFrEF的临床特征和3个月后的结果.
- 为了确定HFpEF是否与急性缺血性中风后的HFrEF相比与更糟糕的预后有关.
主要方法:
- 在2018年1月至2021年1月期间注册的108名有HFpEF或HFrEF的AIS患者的回顾性分析.
- 糟糕的结果被定义为修改后的Rankin尺度得分2-6在3个月.
- 使用单变量和二进制逻辑回归分析来评估预后差异.
主要成果:
- 与HFrEF患者相比,HFpEF患者年龄较大,患慢性病率较高.
- HFpEF与AIS后3个月出现不良结果的风险显著增加相关 (OR4.13,P=0.029).
- 在HFpEF和HFrEF组之间,在出血转化或3个月死亡率方面没有发现显著差异.
结论:
- 与HFrEF患者相比,3个月后,有HFpEF的AIS患者的功能结果明显差.
- 这些发现表明,有AIS的HFpEF患者可能需要专门的监测和管理策略.
- 建议在大型前性研究中进一步验证.
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