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Updated: Jul 7, 2025

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在初始淋巴血管中的VE-cadherin结动力学促进淋巴结转移

Miguel Sáinz-Jaspeado1, Sarah Ring1, Steven T Proulx2,3

  • 1Beijer and Science for Life Laboratories, Department Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

Life science alliance
|December 26, 2023
PubMed
概括

由VEGFA驱动的淋巴血管中的血管内皮 (VE) - cadherin结合拉链,促进癌症转移. 通过VEGFR2突变抑制VE-cadherin碎片化可以减少瘤扩散到淋巴结.

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