在新婚夫妇中,抗生素暴露与夜间睡眠时间和白天嗜睡有关
Lvfen Gu1,2,3,4, Yachao Ni1,4, Baolin Wang1,2,3,4
1School of Public Health, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China.
Environmental science and pollution research international
|December 26, 2023
概括
暴露于抗生素,特别是佛罗芬尼科尔,芬尼科尔和兽医抗生素 (VA),与新婚夫妇的睡眠时间缩短有关. 某些抗生素也增加了白天的嗜睡,性别对这些影响有影响.
科学领域:
- 生殖健康 生殖健康
- 药理学 药理学是指药理学的学科.
- 睡眠医学 睡眠医学
背景情况:
- 关于抗生素暴露对新婚夫妇睡眠模式的影响的研究有限.
- 新婚状态可能代表一个独特的生理和心理调整时期,可能会影响对药物等环境因素的反应.
研究的目的:
- 研究新婚夫妇暴露于各种抗生素和睡眠时间 (周日,周末,平均) 和白天嗜睡之间的关联.
- 探索性别对抗生素暴露对睡眠和嗜睡的影响的调节作用.
主要方法:
- 利用演员-伴侣相互依存度调节模型分析了来自2698名新婚夫妇的数据.
- 评估了对特定抗生素 (佛洛芬尼科尔,芬尼科尔,VA,西普洛克萨,赛多克斯,红色素,四环素) 的暴露,以及它们与睡眠时间和爱普沃思睡眠度量表 (ESS) 分数的相关性.
- 检查了性别作为抗生素暴露和睡眠/嗜睡结果之间的关系的调节者.
主要成果:
- 几乎所有参与者 (99.0%) 接触过至少一种抗生素.
- 暴露于佛罗芬尼科尔,芬尼科尔和兽医抗生素 (VA) 与工作日和平均睡眠时间的减少有显著关联.
- 齐普罗夫洛克萨和赛多克斯暴露与白天睡眠增加相关 (ESS得分更高).
- 性别调节了红色素和四环素对平日睡眠时间和ESS分数的影响.
结论:
- 暴露于抗生素,特别是佛罗芬尼科尔,芬尼科尔和VA,会对新婚夫妇的睡眠时间产生负面影响.
- 某些抗生素,如西普洛素和赛多克斯,与白天睡眠增加有关.
- 在这一群体中,性别在特定抗生素暴露和与睡眠相关的结果之间的关系中起到了缓和作用.
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