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所有原因的过敏反应的基于人口的发病率及其随时间的发展:系统性审查和元分析
Vanessa Pühringer1, Bernd Jilma1, Harald Herkner2
1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Frontiers in allergy
|December 27, 2023
概括
全球所有原因过敏症的发病率约为每年每10万人中约有46例. 这项分析显示,过敏反应率的年增幅令人担忧,强调需要进一步调查.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 过敏研究 研究过敏
背景情况:
- 在不同研究中比较过敏反应的发生率是具有挑战性的,因为方法的差异.
- 准确的全球发病率对于了解过敏反应对公共健康的影响至关重要.
- 以前的研究还没有全面评估全球所有原因过敏反应的趋势.
研究的目的:
- 确定目前全球所有原因过敏症的发病率.
- 调查过敏反应发病率的时间趋势.
- 为了确定影响报告过敏反应率的因素.
主要方法:
- 基于人口的发病率的系统审查和元分析.
- 在四个主要数据库进行文献搜索.
- 协议注册在INPLASY (注册系统审查和元分析协议的国际平台).
主要成果:
- 确定了46个符合条件的文章,产生每年每10万人口约46例的全球发病率.
- 基于过敏诊所或住院治疗的研究报告了较低的发病率.
- 过敏反应的发生率每年显著增加7.4%,在儿童中不太常见.
结论:
- 这项研究提供了迄今为止最准确的全因过敏症发病率的流行病学评估.
- 过敏反应的发病率不断上升,需要进一步研究潜在的原因.
- 研究结果可以为旨在减少过敏反应频率的公共卫生策略提供信息.
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