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评估了四个成年人内脏莱什曼病的病例

Mehmet Çabalak¹, Gülnaz Çulha², Tuğba Kaya²

¹Hatay Mustafa Kemal Üniversitesi Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Hatay, Türkiye.

Turkiye parazitolojii dergisi

|December 27, 2023

概括

由Leishmania infantum引起的内脏莱什曼病 (VL) 可以影响成年人,出现发烧和器官膨胀. 在大多数成人病例中,早期诊断和脂质体安福特里辛-B治疗导致了康复.

科学领域:

传染性疾病传染性疾病
寄生虫学的寄生虫学
内部医学内部医学

背景情况:

由*Leishmania infantum*引起的内脏莱什曼尼病 (VL) 通常在儿童中见到,但也可能发生在成人中.
成人VL病例往往被误诊,最初被怀疑是血液性恶性瘤.
这项研究重点关注了向土耳其医院提交的成人VL患者,突出了诊断和治疗的挑战.

研究的目的:

评估四名成人VL患者的诊断,临床表现,实验室发现和治疗结果.
强调在非特异性症状和血液学异常的成年患者中考虑VL的重要性.
审查成年VL病例的管理和康复,这些病例接受了脂质体安福特里辛-B的治疗.

主要方法:

在2022年1月至4月期间诊断出VL的四名成年患者的回顾性分析.
诊断方法包括临床检查,血清学测试 (IFAT,rK39),RT-PCR和骨髓检查.
治疗涉及脂质体安福特里辛-B (L-AMB).

主要成果:

这四名患者都出现了发烧,疲劳,腹部张张,肝大,贫血,白血病和血小板缺血.
所有患者的血清学结果均为阳性;骨髓和RT-PCR证实*L.婴儿/L.婴儿. 没有感染的感染.
四分之三的患者在L-AMB治疗后完全康复,没有观察到复发.

结论:

在没有免疫抑制的情况下,也应考虑在患有发烧,肝壮症和细胞衰竭的成年患者中考虑内脏莱什曼病.
及时诊断和用L-AMB治疗对于成年人VL是有效的,导致有利的结果.
这项研究强调了VL误诊的可能性,即成年人患有血液性恶性瘤.

关键词:

内脏莱什曼病 - 内脏莱什曼病诊断诊断诊断诊断诊断诊断治疗治疗治疗治疗治疗治疗

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