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刺痛突变通过限制NLRP3激活来减轻乙氨基诱导的急性肝损伤

Zi-Chen Li1, Fang-Fang Xu1, Jiang-Tao Fu2

  • 1Department of Pharmacy, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

International immunopharmacology
|December 27, 2023
PubMed
概括

过量服用乙氨基会导致肝损伤,部分是通过STING途径. 抑制STING或NLRP3可以减少肝损伤和炎症,这表明急性肝损伤的新治疗点.

关键词:
由APAP引起的急性肝损伤.免疫细胞是免疫细胞.炎症 炎症是一种炎症.在NLRP3中,NLRP3是NLRP3中的一个.刺痛是一种刺痛.

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