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Updated: Jul 7, 2025

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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效应器阶段IL-2信号驱动Th1效应器和记忆反应,依赖和独立于TCF-1

Krystal R Charley1,2, Andrew G Ramstead1,2, Joseph G Matous1,2

  • 1Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112.

Journal of immunology (Baltimore, Md. : 1950)
|December 27, 2023
PubMed
概括

干白素-2 (IL-2) 信号传递对CD4+T细胞分化至关重要,促进Th1细胞发育,并在病毒感染期间塑造记忆细胞群. IL-2通过TCF-1依赖和独立的途径影响T细胞命运.

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