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在CD30.CAR-T治疗后,初始的克隆性血液形成加速

Chiraag D Kapadia1, Gerardo Rosas2, Sachin G Thakkar3

  • 1Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, Texas, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.

Cytotherapy
|December 27, 2023
PubMed
概括

化学抗原受体 (CAR) T细胞疗法可能会扩大淋巴瘤患者的先前存在的克隆性血液形成 (CH). 小CH克隆,定义为变异基频率<1%,在CAR-T治疗后显著扩张.

关键词:
在CART-T中,我们可以使用CAR-T.克隆性血液形成 (clonal hematopoiesis) 是一种细胞形成的过程.晚期影响 后期影响淋巴瘤淋巴瘤是什么

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