理想的心血管健康和心血管相关事件:系统性审查和元分析
Femke Te Hoonte1, Merve Spronk1, Qi Sun1
1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.
European journal of preventive cardiology
|December 27, 2023
概括
达到理想的心血管健康 (CVH) 显著降低了心血管疾病 (CVD) 和心脏代谢疾病 (CMD) 的风险. 即使是中度的CVH也能提供保护,这凸显了Life Simple的7对预防疾病的重要性.
科学领域:
- 心血管健康 心血管健康
- 预防性心脏病学 预防性心脏病学
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 和心脏代谢疾病 (CMD) 构成了全球严重的健康负担.
- 促进心血管健康 (CVH) 对于预防这些疾病至关重要.
- 生活简单的7 (LS7) 度量评估理想的CVH,但其与各种CVD和CMD的关联需要全面的总结.
研究的目的:
- 系统地审查和定量综合关于Life Simple的7 (LS7) 和多种心血管疾病和CMD风险之间的联系的证据.
- 提供理想和中间CVH对各种心血管和心脏代谢结果的保护作用的定量总结.
主要方法:
- 从2010年1月到2022年3月,在EMBASE和PubMed进行了系统的文献搜索.
- 包括观察性研究,调查成人理想CVH和CVD/CMD结局之间的关联.
- 数据使用随机效应元分析进行分析,包括59项研究,共有1,881,382名参与者.
主要成果:
- 与CVH差的人相比,具有理想CVH的参与者对各种心血管疾病和CMD的风险明显较低.
- 风险降低在心房动 (HR=0.60) 的40%到心肌梗塞 (HR=0.18) 的82%之间.
- 中级CVH与27-57%的风险降低有关,心房动 (HR=0.73) 和外周动脉疾病 (HR=0.43) 的显着减少.
结论:
- 心血管健康的理想和中等水平都与心血管疾病和心血管疾病的发病率降低有关,而心血管健康水平较差.
- 简单生活的7度指标显示了提高整体CVH的巨大潜力.
- 通过LS7促进CVH可以显著促进预防心血管和心脏代谢疾病.
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