综合症抗生素和养老院医生的抗生素选择对于尿路感染
Lindsay N Taylor1,2,3, Brigid M Wilson4,5, Mriganka Singh6
1University of Wisconsin School of Medicine and Public Health, Madison.
JAMA network open
|December 27, 2023
概括
为养老院临床医生提供尿路抗生素图,改善了针对尿路感染 (UTI) 的活性和最佳抗生素的选择. 传统和加权发病综合征组合抗生素图表都显示出好处,这表明它们在临床实践中的价值.
科学领域:
- 传染性疾病 传染性疾病
- 老年病的医生 老年病的医生
- 临床药房 临床药房
背景情况:
- 在养老院 (NHs) 处方经验性抗生素往往是不理想的.
- 抗生素图书对指导NHs实证抗生素选择的实用性尚未得到充分理解.
研究的目的:
- 评估是否为NH临床医生提供尿路抗生素计可以改善尿路感染 (UTI) 的实证抗生素治疗.
主要方法:
- 一项调查研究利用美国NH临床医生的临床图片.
- 参与者被随机分配使用传统的抗生素图 (TA),加权发病综合征组合抗生素图 (WISCA) 或没有工具.
- 经验性抗生素选择被评估为微生物活性和最佳性.
主要成果:
- 在选择活性和最佳实证抗生素时,TA和WISCA的使用在统计学上优于没有工具.
- 在所有细分组中对活跃和最佳抗生素选择进行比较时,TA和WISCA的表现类似.
- 大多数受访者都是具有广泛NH实践经验的医生.
结论:
- 尿路抗生素图与在模拟NH环境中改善对尿路感染的活性和最佳抗生素的选择有关.
- 虽然抗生素图表格式的整体性能类似,但上下文特异性的影响需要进一步研究.
- 研究结果支持使用抗生素图表来增强NHs的经验性抗生素决策.
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