用于测量血压,握力和肺功能的设备的比较:一个随机交叉研究
Carli Lessof1, Rachel Cooper2,3, Andrew Wong4
1National Centre for Research Methods, University of Southampton, Southampton, United Kingdom.
PloS one
|December 27, 2023
概括
测量血压,握力和肺功能的不同设备显示出显著的差异. 这些差异对于解释纵向研究结果和比较跨研究数据至关重要.
科学领域:
- 生理学 生理学 生理学
- 生物医学工程 生物医学工程
- 流行病学 流行病学
背景情况:
- 纵向人口研究经常评估血压,握力和肺功能.
- 这些研究中使用的测量设备往往有所不同,这会影响数据的一致性.
- 标准化不同设备的测量对于可靠的研究至关重要.
研究的目的:
- 为了比较常用的血压,握力和肺功能测量器件的测量结果.
- 量化不同,并评估不同测量仪器之间的一致性.
- 通知研究人员关于纵向健康数据的潜在差异.
主要方法:
- 采用了一种随机交叉研究设计.
- 118名参与者 (年龄在45-74岁之间) 使用两台血压计,四台手持式动力计和两台螺旋计进行了评估.
- 使用布兰德-阿尔特曼图和多层模型来估计平均差异和一致性极限.
主要成果:
- 密度计显示平均差异为3.9mmHg (静缩) 和1.4mmHg (透缩).
- 与液压/弹仪器相比,电子动力计的抓地强度测量结果更高 (4-5kg的差异).
- 螺旋计显示FEV1的差异很小,但FVC的差异值得注意的是0.47l,其中一个设备的测量值更高.
结论:
- 对于关键的生理功能,常用的设备之间存在显著的测量差异.
- 这些差异在解释个体内变化和进行跨研究比较时需要仔细考虑.
- 灵敏度分析和潜在的校正因子对于协调来自不同测量工具的数据可能是有价值的.
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