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Updated: Jul 7, 2025

Basics of Multivariate Analysis in Neuroimaging Data
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Basics of Multivariate Analysis in Neuroimaging Data

Published on: July 24, 2010

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一种增强的门德尔随机化方法提供了脑成像特征对单个生物银行规模数据集中复杂特征的因果关系

Anyi Yang1,2, Yucheng T Yang1,2, Xing-Ming Zhao1,2,3,4

  • 1Department of Neurology, Zhongshan Hospital and Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, People's Republic of China.

PLoS genetics
|December 27, 2023
PubMed
概括

这项研究引入了带有部分最小平方和拉索回归 (MR-PL) 的门德尔随机化,这是一种分析大型生物库的新方法. 通过使用遗传数据,脑成像和单一队列内的特征,MR-PL准确地识别了复杂疾病的因果风险因素.

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