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Updated: Jul 7, 2025

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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B56δ长期失调的手臂形成了一个动态的PP2A调节接口,加上全球性全ostery和乔丹综合征突变

Cheng-Guo Wu1,2, Vijaya K Balakrishnan1, Ronald A Merrill3

  • 1McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin at Madison, School of Medicine and Public Health, Madison, WI 53705.

Proceedings of the National Academy of Sciences of the United States of America
|December 27, 2023
PubMed
概括

编码为B56δ的PPP2R5D中的突变通过改变蛋白酸酶2A (PP2A) 全酶结构和活性,导致神经系统疾病. 这导致酶功能增加和细胞分裂错误.

关键词:
乔丹综合征 (Jordan's syndrome) 是一种疾病,发生在一个人身上.低温电子显微镜的低温电子显微镜.酸酶是一种酸酶.

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