替代多环芳 (SPAHs) 的发生,来源和健康风险不能被忽视
Xiao Zhang1, Xiaolei Wang2, Weigang Liang1
1College of Water Sciences, Beijing Normal University, Beijing 100875, China; Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.
替代多环芳 (SPAH) 是广泛存在的环境污染物,工业区附近的度更高. 这项研究突出了它们对健康的重大风险,特别是来自像6-N-Chr.这样的特定化合物.
科学领域:
- 环境化学环境化学
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 替代多环芳 (SPAH) 是类似于原始PAH的环境污染物,但研究关注度较低.
- SPAH对人类健康构成重大风险,需要更深入地了解它们的环境存在和来源.
研究的目的:
- 调查10种父PAHs和15种SPAHs的发生,分布和来源.
- 评估与各种环境介质中的SPAHs相关的环境影响和人类健康风险.
主要方法:
- 从高暴露 (工业园区附近) 和低暴露区域收集和分析土壤,水,室内/室外PM2.5和尘埃样本.
- 利用定量结构-活性关系 (QSAR) 模型来预测毒性等效因子 (TEF) 和评估终身致癌风险 (ILCR).
主要成果:
- 在所有介质中,PAH污染在高暴露区域比低暴露区域更严重.
- 化和氧化SPAHs占主导地位,在所有尘埃样本中发现3-OH-BaP和1-OH-Pyr,在自来水中检测到6-N-Chr.
- SPAHs主要来自石油工业和混合燃烧来源;PAHs倾向于从空气沉积到尘埃中.
结论:
- SPAHs对整体PAH污染和相关的健康风险做出了重大贡献,特别是在靠近工业活动的地区.
- 像6-N-Chr和1-Me-Pyr这样的特定SPAH,即使在较低的环境度下,也会带来相当大的致癌风险.
- 这项研究强调了监测和控制SPAHs以减轻人类健康风险的重要性.
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