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Updated: Jul 7, 2025

Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans
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NFE2L1/Nrf1作为神经退行性疾病的潜在治疗点

Kamila Łuczyńska1, Zhengwen Zhang2, Tadeusz Pietras3

  • 1Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, Jastrzebiec, 05-552, Poland; The Second Department of Psychiatry, Institute of Psychiatry and Neurology in Warsaw, 02-957, Warsaw, Poland.

Redox biology
|December 27, 2023
PubMed
概括

蛋白质通过ubiquitin-proteasome系统降解对神经系统的健康至关重要. 核因子-红色素2样bZIP因子1 (NFE2L1/Nrf1) 调节这个系统,并显示神经退行性疾病的治疗潜力.

关键词:
我们的CNC是CNCCNC.NFE2L1 ((Nrf1)) 是一个非金融机构.NFE2L2 ((Nrf2)) 的意思是没有资金.神经保护是一种神经保护.在SKN-1中使用.神经退行性疾病的神经退行性疾病

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