儿童的环境,大脑和行为之间的三重相互作用:ABCD研究
Dongmei Zhi1, Rongtao Jiang2, Godfrey Pearlson3
1State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China.
Biological psychiatry
|December 27, 2023
概括
环境暴露通过影响大脑网络,显著影响儿童的行为. 家庭,邻居和睡眠问题是影响认知能力和心理健康的关键因素,由大脑功能连接介导.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 环境健康 环境健康
背景情况:
- 环境暴露对儿童的行为发展至关重要.
- 连接环境暴露,大脑功能连接和行为的机制尚未得到充分理解.
研究的目的:
- 为了研究全面的环境-大脑-行为三重相互作用.
- 检查大脑功能网络连接 (FNC) 和环境暴露对儿童认知和心理健康行为的预测能力.
主要方法:
- 在青少年大脑认知发展 (ABCD) 研究中,利用了来自7655名儿童的数据的关联,预测和调解分析.
- 评估了41种环境暴露和23种与认知能力和心理健康相关的行为.
- 与英国生物库研究 (N = 20,852) 进行交叉验证的结果.
主要成果:
- 大脑功能网络连接 (FNC) 预测了比心理健康更多的认知能力,其中丘脑和海马是关键.
- 与环境因素相结合的FNC显示了所有行为,特别是心理健康 (r = 0.32-0.63) 的更强的预测能力.
- 家庭和社区的暴露影响了认知能力和心理健康,由FNC调解. 睡眠问题,家庭冲突和不利的学校环境增加了心理健康风险.
结论:
- 揭示了全面的环境-大脑-行为相互作用,突出了认知控制和默认模式网络的预测作用.
- 危急的环境暴露,尤其是睡眠问题,对儿童发育和心理健康有持久的影响.
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