微气泡:用定制的治疗精度彻底改变生物医学应用.
Mohit Kumar1, Devesh Kumar1, Shruti Chopra1
1Department of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University (MRSPTU), Bathinda, Punjab 151001, India.
Current pharmaceutical design
|December 28, 2023
概括
微气泡是先进的药物输送系统,使用超声波在特定地点释放治疗剂. 它们的多功能性支持各种生物医学应用,包括癌症和基因疗法.
科学领域:
- 生物医学工程 生物医学工程
- 纳米技术 纳米技术
- 药物输送系统 药物输送系统
背景情况:
- 在过去的十年中,微气泡研究在生物应用方面取得了重大进展.
- 微气泡是现代药物输送中的动态工具,可实现药物或基因的向输送.
- 超声波触发的微气泡破裂促进了生物活性材料的特定地点的输送.
研究的目的:
- 审查微气泡的组成和生理化学特征.
- 探索创新的生物医学应用,重点是分子成像和向药物/基因输送.
主要方法:
- 使用诸如交联聚合,乳液溶剂蒸发,原子化和复制等方法制备微气泡.
- 制备涉及聚合物溶液,表面活性剂溶液和特定的气体或透剂.
- 方法确保了治疗应用的稳定微气泡的产生.
主要成果:
- 基于微气泡的药物递送利用气体充满的气泡作为治疗剂的载体.
- 这些载体可以装载药物,成像剂或基因以进行有针对性的输送.
- 在引导治疗有效载荷到特定解剖位置的成功应用.
结论:
- 微气泡在生物医学应用中的实用性正在随着新的配方和方法而扩大.
- 微气泡的多功能性允许根据各种医疗需求进行定制.
- 应用包括癌症治疗,心血管治疗和基因治疗.
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