血液学参数作为传染性内心炎患者长期死亡率的预测因素
Sevil Gülaştı1, Cemil Zencir1, Sercan Cayirli2
1Department of Cardiology, Adnan Menderes University School of Medicine, Aydin, Turkey.
概括
入院时的中性粒细胞与淋巴细胞比率 (NLR) 是感染性内心炎 (IE) 患者3年死亡率的强有力的预测指标. 这种可访问的血液测试可以帮助识别高风险个体,以获得更好的长期结果.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 血液学 血液学 血液学
背景情况:
- 传染性内心炎 (IE) 具有显著的死亡和发病风险.
- 早期和准确的风险分层对于管理IE患者至关重要.
- 中性粒细胞与淋巴细胞的比率 (NLR) 是一种随时可用的血液学标志物,与各种疾病的预后不佳有关.
研究的目的:
- 在被诊断患有传染性内心炎的患者中调查实验室参数与3年死亡率之间的关联.
- 确定中性粒细胞与淋巴细胞的比率 (NLR) 是否可以作为IE中长期死亡率的预测标记.
主要方法:
- 对155名确诊IE的成年患者的临床和心声学数据的回顾性分析.
- 评估各种实验室结果,包括血红蛋白,白细胞计数,中性粒细胞,淋巴细胞,血小板,血小板分布宽度,NLR,尿素,肌素,白蛋白,公素和血液培养.
- 统计分析以确定与3年死亡率的显著差异和关联.
主要成果:
- 在IE患者中,整体3年死亡率为54.8%.
- 在存活的患者和没有存活的患者之间,在入院中性粒细胞与淋巴细胞比率 (NLR) 值中观察到显著的差异.
- 更高的入院NLR与3年死亡率的增加密切相关 (P<0.001).
结论:
- 入院中性粒细胞与淋巴细胞比率 (NLR) 是感染性内心炎患者3年死亡率的独立预测指标.
- NLR是一种简单,廉价和广泛可用的血液学参数,可以帮助预测IE的长期死亡率.
- 使用NLR可以提高风险评估,并可能指导IE的临床管理策略.
相关概念视频
01:20Blood Studies for Cardiovascular System I: Cardiac Biomarkers
160
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
160
01:19Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
94
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
94