计算路线:严重COVID-19幸存者的功能性轨迹和长期结果
L U Taniguchi1, M J R Aliberti, M B Dias
1Leandro Utino Taniguchi, Emergency Medicine Discipline, Hospital das Clínicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo, Av Enéas de Carvalho Aguiar 255 Sala 5023, Postal Code: 05403-000, São Paulo, Brazil, e-mail: leandrout@hotmail.com, telephone: 55-11-2661-6336, fax: 55-11-2662-6336.
The journal of nutrition, health & aging
|December 28, 2023
概括
严重COVID-19的幸存者面临着不同的功能恢复路径. 在COVID-19后的较高残疾水平增加了不良结果的风险,影响了长期的健康和认知.
科学领域:
- 关键护理医学 关键护理医学
- 康复医学 康复医学 康复医学
- 传染性疾病 传染性疾病
背景情况:
- 严重的COVID-19幸存者经常经历长时间的康复和潜在的长期健康并发症.
- 了解功能轨迹对于管理COVID-19后的情况和改善患者的治疗结果至关重要.
研究的目的:
- 为了调查重症COVID-19幸存者的功能轨迹,在医院出院后长达一年.
- 评估这些轨迹与不良结果,认知功能和COVID-19后状况之间的关联.
主要方法:
- 一项前性队列研究,涉及422名重症COVID-19幸存者从重症监护室出院.
- 隐性类增长分析被用来识别基于日常生活活动的不同功能轨迹.
- 评估包括残疾状况,认知能力和COVID-19后的状态在出院后的多个时间点.
主要成果:
- 确定了四种功能性轨迹:最小,轻度,中度和严重的残疾.
- 与最小残疾相比,中度和重度的轨迹与1年不良结果的概率增加有显著的关联.
- 后COVID-19状态 (67.5%) 和认知功能与已识别的功能轨迹有关.
结论:
- 严重的COVID-19幸存者表现出不同的功能恢复模式,更高的初始残疾预测更糟糕的长期结果.
- 这些发现凸显了针对性康复干预的必要性,以减轻败血症幸存者的长期不良事件.
- 需要进一步的研究来验证这些发现,并评估康复策略的有效性.
相关概念视频
01:17Classification of Illness
7.5K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
7.5K
01:20COPD: Pathogenesis and Clinical Features
279
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
279
01:15Assumptions of Survival Analysis
133
Survival models analyze the time until one or more events occur, such as death in biological organisms or failure in mechanical systems. These models are widely used across fields like medicine, biology, engineering, and public health to study time-to-event phenomena. To ensure accurate results, survival analysis relies on key assumptions and careful study design.
133
01:30Pneumonia III: Complications and Assessment
231
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
231
01:21Cancer Survival Analysis
355
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
355
01:20Actuarial Approach
79
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
79