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Updated: Jul 7, 2025

Coculture Analysis of Extracellular Protein Interactions Affecting Insulin Secretion by Pancreatic Beta Cells
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在人类胰腺β细胞中对p57KIP2的结构功能分析揭示了双分核定位信号

Lauryn Choleva1, Peng Wang2, Hongtao Liu2

  • 1Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Endocrinology
|December 28, 2023
PubMed
概括

CDKN1C中的突变通过影响细胞循环抑制剂p57KIP2引起儿科内分泌综合征. 这项研究揭示了p57KIP2具有两个核定位序列,这对其在人类β细胞中的功能至关重要.

关键词:
贝克维思-维德曼综合征是什么?贝塔细胞是贝塔细胞的组成部分.糖尿病 糖尿病患者 糖尿病患者

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