对后COVID症状和导致慢性后COVID综合征的倾向因素的分析
Hülya Abalı1, Dilara Demir2, Şule Gül1
1Clinic of Pulmonology, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, University of Health Sciences, İstanbul, Türkiye.
女性性别和特定的放射学发现是慢性后COVID综合征的危险因素. 长期使用 ангиотензин-2 受体抑制剂可能会降低后COVID条件的症状负担.
科学领域:
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
- 公共卫生 公共卫生
背景情况:
- 关于后COVID综合征及其风险因素的知识有限.
- 急性COVID-19可能是致命的,并影响多个器官系统.
研究的目的:
- 为了识别COVID后的症状.
- 为了确定慢性后COVID综合征的危险因素.
主要方法:
- 对254名COVID-19患者进行的前性横截面研究.
- 在发病后5周和12周通过电话审查评估症状.
- 风险因素的分析,包括人口统计,住院和并发症.
主要成果:
- 221名患者患有急性后COVID (APC) 症状,138人患有慢性后COVID (CPC) 症状.
- 疲劳在第5周很常见,头发在第12周脱落.
- 女性性别和特定的放射性发现是CPC的显著风险因素 (p=0.03,p=0.00).
- 长期使用血管激素-2受体抑制剂 (ARB) 与较低的CPC症状数量相关 (p=0.00).
结论:
- 女性性别和放射学发现是慢性后COVID的危险因素.
- 长期使用ARB与慢性后COVID症状负担减少有关.
- 多系统性症状需要针对COVID-19幸存者进行量身定制的长期门诊治疗.
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