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放射性治疗如何影响视网膜

Ceren Gürez¹, Aynur Özen², Özgül Ekmekçioğlu³

¹Ophthalmology Clinic, Beyoglu Eye Training and Research Hospital, Health of Sciences University, Turkey.

World journal of nuclear medicine

|December 28, 2023

概括

放射性 (RAI) 治疗甲状腺功能障碍和甲状腺癌并没有显著影响斑点或视网膜神经纤维层厚度. 这项研究表明RAI治疗对视网膜层是安全的.

科学领域:

眼科医生眼科眼科
内分泌学在内分泌学.
核医学就是核医学.

背景情况:

放射性 (RAI) 治疗是甲状腺功能障碍和甲状腺癌的标准治疗方法.
对RAI治疗的潜在眼部副作用需要进行调查,特别是在视网膜结构方面.

研究的目的:

在接受RAI治疗的患者中,量化评估斑点和视网膜神经纤维层 (RNFL) 厚度.
评估RAI对甲状腺功能过高和甲状腺癌患者视网膜健康的影响.

主要方法:

这是一项前性研究,涉及40名患有甲状腺功能障碍或甲状腺癌的患者 (80只眼睛),接受RAI治疗.
眼科检查和光学连贯性断层扫描 (OCT) 对黄斑和RNFL厚度的测量在RAI前进行,并在RAI后的1,6和12个月进行.
包括没有先前存在眼部病理的患者.

主要成果:

在甲状腺功能升高或甲状腺癌组中,在RAI治疗前和后的斑点厚度或RNFL厚度中没有观察到统计学上显著的差异.
在这两组研究中,年龄和性别分布是可比的.
没有检测到对视网膜层的不良影响.

结论:

对于甲状腺功能障碍和甲状腺癌的RAI治疗似乎不会对视网膜层造成重大伤害.
这些发现表明,RAI是一种安全的治疗方式,涉及诸如斑点和RNFL等眼睛结构.

关键词:

马库拉 (Macula) 是一个斑点.甲状腺功能过强症甲状腺功能过强症神经纤维层是一种神经纤维层.放射性是一种放射性.甲状腺癌是一种癌症.

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